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pentobarbital will lessen the extent or effect of suvorexant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Powerful CYP3A4 inducers could minimize suvorexant efficacy; if enhanced suvorexant dose required, usually do not exceed 20 mg/daypentobarbital will lower the extent or influence of finasteride by affecting hepat